Research Use Only

These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.

Description:

KPV is a tripeptide (lysine – proline – valine) obtained from the alpha-melanocyte stimulating hormone (Alpha-MSH). This natural neuroregulatory peptide is known for its anti-inflammatory and antimicrobial properties. In different forms of the application, it can be useful for treating various states based on inflammation. If used in topical cream form, it can potentially prevent further development of eczema, psoriasis and acne. The oral application could be significant in treating inflammatory diseases of hoses such as ulcerative colitis, Crohn’s disease and inflammatory intestine syndrome. Injection use manifests overall anti-inflammatory effects. According to various studies, KPV could potentially accelerate wound healing and reduce the possibility of scarring after surgery. This peptide expresses all the mentioned effects modified and significantly improved in relation to the original molecule.

Alfa-Melanocyte Stimulative hormone is the original natural molecule, with KPV as the derivative. Its crucial function is anti-inflammatory potential, achieved in several different ways. One of them is through melanocortine receptors (MC-R), localized on different central and peripheral nervous system cells.

Even if this property can be used in treating various diseases, Alfa MSH has been avoided for increasing melanin secretion, potentially causing skin cancer. However, KPV is the least active form in melanin production, reducing this risk significantly. Modifying chemical construction improves anti-inflammatory and other positive effects, but also reduces unwanted actions. The anti-inflammatory effect could be used in treating some skin conditions such as psoriasis, acne, and eczema. Many scientific studies assume that KPV can reduce the cytokines expression, and the activity of many inflammatory cells, reducing hypercheralatosis. In addition, angiogenesis (the process of creating new blood vessels) maintains the inflammation active and emphasizes it. Prevention of further angiogenesis is another mechanism of action.
The main property may be helpful in treating digestive problems (inflammatory bowel diseases such as Crohn’s disease, ulcerative colitis, and others). Based on a similar mechanism of action (reducing the production of TNF alpha and pro-inflammatory cytokines), KPV can accelerate the healing of wounds, localized on mucosa, restore epithelial cells, and thus alleviate symptoms such as diarrhea and severe pain.

In addition to the above properties, the peptide has the ability to modulate the immune response, accelerating regeneration mechanisms. Therefore, wounds after surgery heal faster without scarring. The peptide could also achieve antimicrobial activity and improve antifungal response, reducing the risk of wound infection. This property is also achieved by enhancing collagen synthesis, which results in rapid recovery.

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